Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula

Authors
Marquez, B Verdier-Pinard, P Hamel, E Gerwick, WH
Citation
B. Marquez et al., Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula, PHYTOCHEM, 49(8), 1998, pp. 2387-2389
Citations number
7
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
49
Issue
8
Year of publication
1998
Pages
2387 - 2389
Database
ISI
SICI code
0031-9422(199812)49:8<2387:CDAAAF>2.0.ZU;2-R
Abstract
Curacin D is a novel brine shrimp toxic metabolite isolated from a Virgin I slands collection of the marine cyanobacterium Lyngbya majuscula. Structure elucidation of curacin D was accomplished through multidimensional NMR, GC /MS, and comparisons with curacin A. Curacin D provides new insights into s tructure-activity relationships iii this natural product class as well as s ome aspects of the likely biosynthetic pathway of the curacins. (C) 1998 El sevier Science Ltd. All rights reserved.