Liquid microchannels on structured surfaces are built up using a wettabilit
y pattern consisting of hydrophilic stripes on a hydrophobic substrate, The
se channels undergo a shape instability at a certain amount of adsorbed vol
ume, from a homogeneous state with a spatially constant cross section to a
state with a single bulge. This instability is quite different from the cla
ssical Rayleigh Plateau instability and represents a bifurcation between tw
o different morphologies of constant mean curvature. The bulge state can be
used to construct channel networks that could be used as fluid microchips
or microreactors.