Simultaneous occurrence of a supra- and an infratentorial glioma in a patient with Ollier's disease: more evidence for non-mesodermal tumor predisposition in multiple enchondromatosis
S. Hofman et al., Simultaneous occurrence of a supra- and an infratentorial glioma in a patient with Ollier's disease: more evidence for non-mesodermal tumor predisposition in multiple enchondromatosis, SKELETAL RA, 27(12), 1998, pp. 688-691
A case is presented in which two neuro-ectodermal tumors, an infra- and a s
upratentorial glioma, developed in a young man with multiple enchondromatos
is of Ollier's disease. This is the third such case of multifocal low-grade
glioma in Ollier's disease, suggesting a predisposition for non-mesodermal
tumors in Ollier's disease. The related condition of multiple enchondromat
osis and hemangiomas (Maffucci's syndrome) is well known for its malignant
potential, developing both mesodermal and non-mesodermal tumors. Along with
other authors, we support the concept of two variants of the same disease
with a predisposition to development of tumors from various germ layers.