Regio- and diastereoselective boron-mediated aldol reactions of chiral alpha,beta,gamma,delta-unsaturated N-acyloxazolidinones

Authors
Takacs, JM Jaber, MR Swanson, BJ Mehrman, SJ
Citation
Jm. Takacs et al., Regio- and diastereoselective boron-mediated aldol reactions of chiral alpha,beta,gamma,delta-unsaturated N-acyloxazolidinones, TETRAHEDR-A, 9(24), 1998, pp. 4313-4324
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
9
Issue
24
Year of publication
1998
Pages
4313 - 4324
Database
ISI
SICI code
0957-4166(199812)9:24<4313:RADBAR>2.0.ZU;2-9
Abstract
Chiral N-acyloxazolidinones derived from conjugated dienoic acids undergo b oron-mediated aldol condensation in good yield and with high regio- and dia stereoselectivity to provide a convenient method for introducing a 1,3-dien e subunit. The condensation of a homologous triene derivative is also descr ibed. (C) 1998 Elsevier Science Ltd. All rights reserved.