Synthesis of ornithine lactams via diastereoselective photocyclization of 2-amino-4-oxo-4-phenyl-butanoyl amines

Authors
Lindemann, U Wulff-Molder, D Wessig, P
Citation
U. Lindemann et al., Synthesis of ornithine lactams via diastereoselective photocyclization of 2-amino-4-oxo-4-phenyl-butanoyl amines, TETRAHEDR-A, 9(24), 1998, pp. 4459-4473
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
9
Issue
24
Year of publication
1998
Pages
4459 - 4473
Database
ISI
SICI code
0957-4166(199812)9:24<4459:SOOLVD>2.0.ZU;2-1
Abstract
The diastereoselective synthesis of ornithine lactams 6-9 via photoinduced E-hydrogen abstraction followed by cyclization of the corresponding 1,6-bir adicals is described. A highly asymmetric 1,4-induction is observed. (C) 19 98 Elsevier Science Ltd. All rights reserved.