Substantial progress has been made in implementing routine infant hepatitis
B vaccination in the United States. However, in 1996, an estimated 65 000
acute hepatitis B cases occurred, the majority of which were among young ad
ults in high-risk groups. Recent surveys have found very low vaccination co
verage among several high-risk groups, including men who have sex with men
and patients with sexually transmitted diseases (STDs). Targeted vaccinatio
n of persons with risk factors for hepatitis B virus (HBV) infection can be
provided in a variety of settings including family planning clinics, STD c
linics, drug treatment centres, detention centres, jails and prisons. Howev
er, vaccination programmes have been infrequently implemented in these sett
ings and the majority of persons with acute hepatitis B cases have had a mi
ssed opportunity for vaccination in the past. Thus. in order to accelerate
elimination of HBV transmission in the United States, increased efforts are
needed to implement effective hepatitis B vaccination programmes targeted
to adolescents and adults in high-risk groups. (C) 1998 Published by Elsevi
er Science Ltd. All rights reserved.