An increase of depressive symptoms in fibromyalgia patients has been noted
in a number of studies. The etiologic significance of this finding remains,
however, controversial. We suggest that a subgroup of patients with this s
ymptom combination may be pragmatically classified as suffering from somati
zed depression. Clinical indicators such as a family history of depressive
disorders, circadian disturbances, pronounced loss of appetite or libido, a
nd chronic psychosocial stressors should be assessed and, if present, promp
t the initiation of psychiatric evaluation and treatment including pharmaco
- and psychotherapeutic modalities. Other psychiatric diseases arising in t
he differential diagnosis of fibromyalgia are discussed.