IN-SITU DETERMINATION OF PHENYLPYRUVATE IN URINE USING A PHENYLPYRUVATE-SELECTIVE MEMBRANE-ELECTRODE CONSTRUCTED WITH A HEPTYL-4-TRIFLUOROACETYLBENZOATE NEUTRAL CARRIER

Authors
WATANABE K NOGUCHI O OKADA K KATSU T
Citation
K. Watanabe et al., IN-SITU DETERMINATION OF PHENYLPYRUVATE IN URINE USING A PHENYLPYRUVATE-SELECTIVE MEMBRANE-ELECTRODE CONSTRUCTED WITH A HEPTYL-4-TRIFLUOROACETYLBENZOATE NEUTRAL CARRIER, Analytical sciences, 13(2), 1997, pp. 209-212
Citations number
31
Categorie Soggetti
Chemistry Analytical
Journal title
Analytical sciences → ACNP
ISSN journal
09106340
Volume
13
Issue
2
Year of publication
1997
Pages
209 - 212
Database
ISI
SICI code
0910-6340(1997)13:2<209:IDOPIU>2.0.ZU;2-X
Abstract
We constructed a phenylpyruvate-selective electrode using heptyl-4-tri fluoroacetylbenzoate as a neutral carrier. The electrode permitted the determination of phenylpyruvate in urine in situ. Its sensitivity spa nned the urinary levels of phenylpyruvate (2-12 mM) reported for pheny lketonuric patients. The results compared favorably with those obtaine d by colorimetry.