We previously described the augmentation of sensory nerve action potential
amplitudes after near and remote isometric muscle contraction. In this stud
y, we wished to determine if the sensory cortex was involved in this proces
s. In this prospective, intrinsically controlled study, we studied threshol
d somatosensory evoked potentials in 12 normal subjects with stimulation of
the median nerve at 5.1 Hz. The subjects were tested during the following
conditions: baseline, 25%, and 75% maximum isometric abductor digiti minimi
contraction for 4 min. Each of these conditions was recorded before, durin
g, and 4 min and 8 min after contraction. Results showed that at 25% contra
ction, there was a significant temporal increase in N9 amplitude (2.1-2.6 m
u V; P = 0.05, analysis of variance, repeated measures) and a decrease in N
20 amplitude with 75% contraction (1.9-1.6 mu V; P = 0.03, analysis of vari
ance, repeated measure). No significant changes were noted in the spinal co
rd or brainstem recordings. In conclusion, it appears that augmentation of
the brachial plexus peripheral nervous system recording occurs concurrently
with central inhibitory gating. The possibility of peripheral nervous syst
em adaptability will be discussed.