PH, HEALING RATE AND SYMPTOM RELIEF IN ACID-RELATED DISEASES

Suppression of gastric acid secretion is widely used and logical for t he treatment of acid-related diseases. Healing of duodenal ulcer, gast ric ulcer and gastroesophageal reflux disease is correlated significan tly with the degree and the duration of suppression of intragastric ac idity over 24 hours and with the length of the treatment. To date, pro ton pump inhibitors are the most effective agents among the currently available antisecretory drugs in offering the highest healing rate and fastest resolution of symptoms. Combinations of an antisecretory drug with one or more antimicrobial agents accelerate healing of peptic ul cers.