Kj. Vanhoeck et al., A RETROSPECTIVE EPIDEMIOLOGIC-STUDY OF BACTERIAL-MENINGITIS IN AN URBAN AREA IN BELGIUM, European journal of pediatrics, 156(4), 1997, pp. 288-291
In order to obtain epidemiological data on the incidence of bacterial
meningitis (BM) before the systematic introduction of vaccination agai
nst Haemophilus influenzae type b, a retrospective study of 124 childr
en with proven BM was performed in an urban area in Belgium. N. mening
itidis was the most prevalent cause, followed by H. influenzae and S.
pneumoniae. Over a period of 6 years the incidence of BM increased ten
fold, mainly due to an increase in N. meningitidis. The median age of
the children with BM was 17 months and 35% of those with H. influenza
e were younger than 1 year. Significant risk factors for BM as a whole
were: age under 1 year, male gender, non-Caucasian descent and winter
time. These findings may have implications for future vaccination pol
icy in Belgium. Conclusion Future vaccination schemes in Belgium shoul
d take into account that N. meningitis was the prevalent cause of bact
erial meningitis and that certain factors increase the risk for develo
ping bacterial meningitis.