Pericardial tamponade as the first manifestation of dermatopolymyositis

Pericardial involvement in polymyositis and dermatomyositis (PM/DM) is rare , usually asymptomatic and exceptionally part of the initial presentation. We describe a 37-year-old patient hospitalized for overt acute pericarditis , revealing dermatomyositis, which to our knowledge has not been previously reported. Pericardial puncture relieved the patient, The pericardial fluid was citrine yellow, exsudative, and mainly contained lymphocytes. Search f or LE cells and anti-DNA antibodies was negative, whereas the antinuclear a ntibodies and the rheumatoid factor were present in the pericardial fluid. A biopsy of the pericardium showed a non-specific chronic inflammatory stat e and the search for an etiology was negative, There was no sign of tubercu losis, systemic lupus, nor neoplasia, Moreover bacteriological cultures and HIV serology were negative. After pericardiostomy associated with corticos teroid therapy at the dose of 1 mg/kg/day, outcome was good with a resoluti on of the pericarditis confirmed at one-gear follow-up. Since pericardial t amponade, even though rare, may be fatal in a patient with dermatomyositis, we emphasize that a two dimensional echocardiographic study should be perf ormed in all patient presenting with dermatopolymositis.