Adequate nutritional intervention in diarrhoeal disease in children is cruc
ial in obtaining optimal control of a disorder that may become life-threate
ning. During recent years, important advances have been made in our underst
anding of the pathophysiology of diarrhoeal states, in the formulation of o
ral rehydration solutions and in the role of micro- and macronutrients in d
iarrhoeal disorders. This chapter outlines some of the relevant concepts in
the pathophysiology of diarrhoeal disease and provides a rationale for nut
ritional intervention. Guidelines for nutritional management in the setting
s of acute-onset diarrhoea, post-enteritis protracted diarrhoea and chronic
non-specific diarrhoea are provided, mostly based on controlled clinical t
rials and meta-analyses of evidence-based medicine.