Design, synthesis and biological activity of novel herbicides targeted ALS(XII) - Quantitative structure-activity relationships of herbicidal 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonanilides

Authors
Yang, GF Liu, HY Yang, XF Yang, HZ
Citation
Gf. Yang et al., Design, synthesis and biological activity of novel herbicides targeted ALS(XII) - Quantitative structure-activity relationships of herbicidal 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonanilides, CHIN J CHEM, 16(6), 1998, pp. 521-527
Citations number
12
Categorie Soggetti
Chemistry
Journal title
CHINESE JOURNAL OF CHEMISTRY
ISSN journal
1001604X → ACNP
Volume
16
Issue
6
Year of publication
1998
Pages
521 - 527
Database
ISI
SICI code
1001-604X(199811)16:6<521:DSABAO>2.0.ZU;2-H
Abstract
The herbicidal activities of a series of 1,2,4-triazolo[1,5-a]pyrimidine-2- sulfonanilides containing various substituents on the benzene ring were qua ntitatively analyzed with physicochemical parameters by using Hansch-Fujita method. Variations in the activity were parabolically related to electroni c parameters with the optimum pK(a) value being about 6.93. The hydrophobic factor in addition to the electronic property seemed to have important eff ect on the activity.