M. Soheilian et al., SURGICAL-MANAGEMENT OF TRAUMATIC RETINAL-DETACHMENT WITH PERFLUOROCARBON LIQUID, International ophtalmology, 20(5), 1997, pp. 241-249
Background: To evaluate the effect of perfluoroperhydrophenanthrene on
the outcome of traumatic retinal detachment with proliferative vitreo
retinopathy, a retrospective study of 111 patients was performed at 35
tertiary care centers, both private practice and institutional. We be
lieved that perfluoroperhydrophenanthrene would assist in manipulating
the retina during surgery, removing intraocular foreign bodies, drain
ing suprachoroidal hemorrhage, and reattaching the retina because of t
he perfluorocarbon's high specific gravity. Methods: Of the 700 patien
ts in the Vitreon study group, 111 with a history of trauma (109 had r
etinal detachment, 50 had proliferative vitreoretinopathy) were chosen
for this study. Perfluoroperhydrophenanthrene was used intraoperative
ly to manipulate the retina hydrokinetically, remove intraocular forei
gn bodies, drain suprachoroidal hemorrhage, and to reattach the retina
in the case of giant tears. Results: Logistic multiple regression ana
lysis was used to identify factors as being predictive of poor visual
outcome. Factors predictive of poor visual outcome were: type of traum
a (p = 0.0065) (ruptured globe); presence of giant retinal tear (p = 0
.0253); and low preoperative visual acuity (p = 0.044). At the last fo
llow-up examination, the reattachment rate was 75.6% (i.e., 84 eyes).
Of those 84 eyes, 55 (49.5%) had achieved a visual acuity of greater t
han or equal to 5/200 and 34 (30.6%) had a visual acuity of greater th
an or equal to 20/200. In cases complicated by proliferative vitreoret
inopathy, the final reattachment rate was 66%, with 40% of the eyes st
udied obtaining a visual acuity of greater than or equal to 5/200. Con
clusions: Perfluoroperhydrophenanthrene has been used intraoperatively
in the management of traumatic retinal detachments without any appare
nt ill effects.