Reversal of bone marrow fibrosis in idiopathic myelofibrosis after treatment with alpha-interferon

Authors
Domingues, MA Haepers, ATC Massaut, IHB Vassallo, J Lorand-Metze, I
Citation
Ma. Domingues et al., Reversal of bone marrow fibrosis in idiopathic myelofibrosis after treatment with alpha-interferon, HAEMATOLOG, 83(12), 1998, pp. 1124-1125
Citations number
9
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
HAEMATOLOGICA
ISSN journal
03906078 → ACNP
Volume
83
Issue
12
Year of publication
1998
Pages
1124 - 1125
Database
ISI
SICI code
0390-6078(199812)83:12<1124:ROBMFI>2.0.ZU;2-7
Abstract
A 14-year-old boy presenting with primary myelofibrosis (MMM) was treated w ith alpha-interferon (IFN). After 6 months his spleen was no longer palpabl e and blood counts had returned to normal. A reversal of bone marrow fibros is was histologically documented. Although improvement in symptoms and bloo d counts has been reported, this is only the second description of reversal of bone marrow fibrosis in MMM after treatment.