Cardiac malignant pheochromocytoma with bone metastases

Citation
A. Arai et al., Cardiac malignant pheochromocytoma with bone metastases, INTERN MED, 37(11), 1998, pp. 940-944
Citations number
24
Categorie Soggetti
General & Internal Medicine
Journal title
INTERNAL MEDICINE
ISSN journal
09182918 → ACNP
Volume
37
Issue
11
Year of publication
1998
Pages
940 - 944
Database
ISI
SICI code
0918-2918(199811)37:11<940:CMPWBM>2.0.ZU;2-M
Abstract
A patient with malignant cardiac pheochromocytoma with bone metastases is d escribed. The primary tumor was located between the pulmonary trunk and the left atrium, while metastatic lesions were found in the iliac bones. Treat ments with antihypertensive agents, alpha-methylparatyrosine, and combinati on chemotherapy with cyclophosphamide, vincristine, and dacarbazine partial ly improved the patient's symptoms, catecholamine levels, and the metastati c lesion of the iliac bones. However, the primary tumor in the heart progre ssively increased in size and the patient died of disseminated intravascula r coagulation and other various complications about 4 years after the diagn osis of the disease.