ENANTIOSEPARATION OF 14 O-ETHYL O-PHENYL N-ISOPROPYL PHOSPHOROAMIDOTHIOATES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY ON A CHIRAL STATIONARY-PHASE

Authors
GAO RY YANG GS YANG HZ CHEN ZY WANG QS
Citation
Ry. Gao et al., ENANTIOSEPARATION OF 14 O-ETHYL O-PHENYL N-ISOPROPYL PHOSPHOROAMIDOTHIOATES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY ON A CHIRAL STATIONARY-PHASE, Journal of chromatography, 763(1-2), 1997, pp. 125-128
Citations number
7
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Journal of chromatography → ACNP
Volume
763
Issue
1-2
Year of publication
1997
Pages
125 - 128
Database
ISI
SICI code
Abstract
A series of fourteen O-ethyl O-phenyl N-isopropyl phosphoroamidothioat e enantiomers containing a phosphorus atom as a chiral center have bee n separated by high-performance liquid chromatography on a Pirkle mode l chiral stationary phase. Chromatography data, the capacity factor (k ') and the separation factor (alpha) of all solutes are presented. The influence of chromatographic conditions was investigated. The probabl e mechanism for chiral recognition is proposed.