Lipase-catalyzed kinetic resolution of 4-hydroxy-5-dodecynonitrile and itsapplication to facile synthesis of a cupreous chafer beetle sex pheromone

Authors
Fukusaki, EI Satoda, S Senda, S Omata, T
Citation
Ei. Fukusaki et al., Lipase-catalyzed kinetic resolution of 4-hydroxy-5-dodecynonitrile and itsapplication to facile synthesis of a cupreous chafer beetle sex pheromone, J FERM BIOE, 86(5), 1998, pp. 508-509
Citations number
8
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
JOURNAL OF FERMENTATION AND BIOENGINEERING
ISSN journal
0922338X → ACNP
Volume
86
Issue
5
Year of publication
1998
Pages
508 - 509
Database
ISI
SICI code
0922-338X(1998)86:5<508:LKRO4A>2.0.ZU;2-8
Abstract
A facile synthetic method for a cupreous chafer beetle sex pheromone (R,Z)- (-)-5-(1-octenyl)oxacyclopenlan-2-one has been developed by employing lipas e-catalyzed enantioselective acylation of racemic 4-hydroxy-5-dodecynonitri le in an organic solvent.