Case report: Helicobacter pylori-induced lymphonodular hyperplasia: A new cause of gastric outlet obstruction

A 30-year-old female was seen with symptoms and radiological evidence of ga stric outlet obstruction. Endoscopic examination revealed findings suggesti ve of gastric outlet obstruction with nodularity of the antral mucosa leadi ng to deformity of the pylorus. Endoscopic biopsies from the nodular antral mucosa showed presence of Helicobacter pylori-induced lymphonodular hyperp lasia without evidence of mucosa-associated lymphoid tissue lymphoma. Anti- H. pylori therapy resulted in eradication of the H. pylori infection and th e signs and symptoms of gastric outlet obstruction. The case demonstrates t hat H. pylori-induced lymphonodular hyperplasia can also cause gastric outl et obstruction. We believe this is the first such case to be reported.