Synthesis and reduction of thieno[2 ',3 '(3 ',2 ' or 3 ',4 '): 5,6]-azocino[2,1-a]isoindole-7,13-diones

Authors
Othman, M Pigeon, P Decroix, B
Citation
M. Othman et al., Synthesis and reduction of thieno[2 ',3 '(3 ',2 ' or 3 ',4 '): 5,6]-azocino[2,1-a]isoindole-7,13-diones, J HETERO CH, 35(6), 1998, pp. 1429-1433
Citations number
8
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022152X → ACNP
Volume
35
Issue
6
Year of publication
1998
Pages
1429 - 1433
Database
ISI
SICI code
0022-152X(199811/12)35:6<1429:SAROT'>2.0.ZU;2-S
Abstract
A synthesis of the thieno[2',3'(3',2' or 3',4'):5,6]azocino[2,1-a]isoindole -7,13-diones 6a-c was developed from N-thienylethylphfhalimides 3a-c using a Wittig reaction followed by a Friedel-Crafts cyclization of acetic acid d erivatives 5a-c. Reduction of ketones 6a-c into alcohols 7a-c was stereospe cific.