Background The use of computed tomography (CT) in acute left colonic d
iverticulitis remains controversial. The purpose of this study was to
define the value of CT both during the acute phase of inflammation and
, later, to indicate secondary complications after successful medical
treatment. Methods Some 423 patients with radiologically or histologic
ally proven diverticulitis were studied prospectively from 1986 to 199
5. Diverticulitis was considered moderate when CT showed localized thi
ckening of the colonic wall (5 mm or more) and inflammation of pericol
ic fat; it was considered severe when abscess and/or extraluminal air
and/or extraluminal contrast were observed. Results The sensitivity of
CT was 97 per cent. Of 42 patients who failed conservative treatment,
32 had severe diverticulitis on CT, compared with 74 (24 per cent) of
303 who had successful conservative treatment (P < 0.0001). After a m
edian follow-up of 46 months, 60 (20 per cent) of 300 patients had sec
ondary complications despite initially successful conservative treatme
nt: 28 (47 per cent) of these had initial severe diverticulitis on CT
compared with 44 (19 per cent) of 236 patients who had no complication
s (P < 0.0001). Conclusion Abscess formation and extracolonic contrast
or gas are findings that may be used to predict failure of medical tr
eatment during the first admission and a high risk of secondary compli
cations after initially successful medical management of acute diverti
culitis.