Objective: To compare the results of Burch colposuspension in premenopausal
and postmenopausal women with urinary stress incontinence (USI). Methods:
A total of 85 women with urodynamic diagnosis of genuine urinary stress inc
ontinence were divided into two groups, according to their menstrual status
(premenopausal and postmenopausal group). All of them underwent the Burch
colposuspension procedure. Clinical and urodynamic data were compared preop
eratively and postoperatively and between the two groups. Results: Cure rat
e was significantly higher after Burch colposuspension in the premenopausal
as compared to the postmenopausal patients (90.9 vs 73.1%, respectively, P
< 0.01). A significant reduction of the diurnal and nocturnal frequency an
d urgency was noted in both groups postoperatively. The reduction of urgenc
y was more prominent in the premenopausal women (P < 0.001). There were no
statistically significant differences between the preoperative and postoper
ative values of bladder capacity, residual volume, maximal voiding pressure
, peak flow rate, absolute urethral length, functional urethral length, ure
thral pressure and maximum urethral closure pressure both preoperatively an
d postoperatively within the groups and between the two groups. Comparing t
he two groups postoperatively, the pressure transmission ratios in the post
menopausal women were found to be significantly lower in the middle two qua
rters of the urethra as compared to the premenopausal patients (P < 0.001).
Conclusion: Burch colposuspension for urinary stress incontinence has bett
er cure rate in premenopausal than in postmenopausal women. Nevertheless, t
he above procedure remains an acceptable method for treatment of USI in pos
tmenopausal patients. (C) 1998 Elsevier Science Ireland Ltd. All rights res
erved.