The capacity of older men and women to adapt to increased levels of physica
l activity is preserved, even in the most elderly. Aerobic exercise results
in improvements in functional capacity and reduced risk of developing Type
II diabetes in the elderly. High-intensity resistance training (above 60%
of the one repetition maximum! has been demonstrated to cause large increas
es in strength in the elderly. In addition, resistance training result in s
ignificant increases in muscle size in elderly men and women. Resistance tr
aining has also been shown to significantly increase energy requirements an
d insulin action of the elderly. Purpose: We have recently demonstrated tha
t resistance training has a positive effect on multiple risk factors for os
teoporotic fracture in previously sedentary postmenopausal women. Methods:
Because the sedentary lifestyle of a long-term care facility may exacerbate
losses of muscle function, we have applied this same training program to f
rail, institutionalized elderly men and women. Results: In a population of
100 nursing home residents, a randomly assigned high-intensity strength-tra
ining program resulted in significant gains in strength and functional stat
us. In addition, spontaneous activity, measured by activity monitors, incre
ased significantly in those participating in the exercise program whereas t
hew was no change in the sedentary control group. Before the strength train
ing intervention, the relationship of whole body potassium and leg strength
was seen to be relatively weak (r(2) = 0.29, P < 0.001), indicating that i
n the very old, muscle mass is an important but not the only determining fa
ctor of functional status. Conclusions: Thus, exercise may minimize or reve
rse the syndrome of physical frailty, which is so prevalent among the most
elderly. Because of their low functional status and high incidence of chron
ic disease, there is no segment of the population that can benefit more fro
m exercise than the elderly.