Osteoporosis is a major public health problem that is characterized by low
bone mass and increased susceptibility to fractures, primarily of the hip,
spine, and wrist. It is estimated to cause 1.5 million fractures annually i
n the United States in people aged 50 yr and older. Physical activity, part
icularly weight-bearing exercise, is thought to provide the mechanical stim
uli or "loading" important for the maintenance and improvement of bone heal
th, whereas physical inactivity has been implicated in bone loss and its as
sociated health costs. Both aerobic and resistance training exercise can pr
ovide weight-bearing stimulus to bone, yet research indicates that resistan
ce training may have a more profound site specific effect than aerobic exer
cise. Over the past 10 years, nearly two dozen cross-sectional and longitud
inal studies have shown a direct and positive relationship between the effe
cts of resistance training and bone density. Conversely, a handful of other
studies have reported little or no effect on bone density. However, these
results may be partially attributable to the study design, intensity and du
ration of the exercise protocol, and the bone density measurement technique
s used. High-intensity resistance training, in contrast to traditional phar
macological and nutritional approaches for improving bone health in older a
dults, has the added benefit of influencing multiple risk factors for osteo
porosis including improved strength and balance and increased muscle mass.