DNA microarrays in drug discovery and development

Authors
Debouck, C Goodfellow, PN
Citation
C. Debouck et Pn. Goodfellow, DNA microarrays in drug discovery and development, NAT GENET, 21, 1999, pp. 48-50
Citations number
19
Categorie Soggetti
Molecular Biology & Genetics
Journal title
NATURE GENETICS
ISSN journal
10614036 → ACNP
Volume
21
Year of publication
1999
Supplement
S
Pages
48 - 50
Database
ISI
SICI code
1061-4036(199901)21:<48:DMIDDA>2.0.ZU;2-C
Abstract
DNA microarrays can be used to measure the expression patterns of thousands :of genes: in p8rallel, generating clues to gene function that can help to identify appropriate targets for therapeutic intervention. They:can also be used to monitor changes in gene expression in response to drug treatments. Were, we discuss the-different ways in which microarray analysis is likely to affect drug discovery.