The SWISS-2DPAGE database: what has changed during the last year

SWISS-2DPAGE (http://www.expasy.ch/ch2d/ ) is an annotated two-dimensional polyacrylamide gel electrophoresis (2-D PAGE) database established in 1993. The current release contains 21 reference maps from human and mouse biolog ical samples, as well as from Saccharomyces cerevisiae, Escherichia coli an d Dictyostelium discoideum origin. These reference maps now have 2480 ident ified spots, corresponding to 528 separate protein entries in the database, in addition to virtual entries for each SWISS-PROT sequence. During the la st year, the SWISS-2DPAGE has undergone major changes. Six new maps have be en added, and new functions to access the data have been provided through t he ExPASy server. Finally, an important change concerns the database fundin g source.