This study investigated the influence of acupuncture stimulation on th
e salivary secretion of eight healthy subjects. The salivary flow of e
ach subject was measured before, during and after every acupuncture se
ssion. The unstimulated, chewing-stimulated and citric acid-stimulated
flows were investigated, in combination with manual and electrically
stimulated acupuncture. The results showed a significant increase of t
he unstimulated salivary flow both during and after the manual acupunc
ture stimulation as compared to baseline levels. There was no effect o
n the unstimulated salivary flow with electro-acupuncture. The stimula
ted salivary flow was not affected by manual acupuncture, while the el
ectrically stimulated acupuncture led to a significant decrease of the
chewing-stimulated salivary flow. The improvement of the unstimulated
salivary secretion in healthy subjects was in accordance with our pre
vious findings in xerostomic patients. It is possible that the salivar
y secretion is influenced by the augmented release of neuropeptides ca
used by acupuncture. Some neuropeptides have been shown to affect sali
vary secretion as well as capillary blood flow.