Medical termination of gestation in the female dog

This literature review describes the principal protocols which can be used to medically terminate gestation in the female dog. The use of oestradiol b enzoate, at the present time, is limited due to the necessity of administra tion in the days which follow mating and due to the number of uterine disea ses which have been observed. The administration of prostaglandin F2 alpha (PGF2 alpha) analogue represents an interesting alternative treatment with high innocuity. However, its use is disagreeable due to vomiting, diarrhoea and ptyalism wh ich are observed each time the drug is administered. Ergolin derivatives, a s for PGF2 alpha, can be used in late gestation(35 d pose-mating) and provi de high innocuity and efficacy whix-ch appears to be satisfactory, however this should be confirmed using a large number of treat ed dogs. Aglepristone is noteworthy by its large spectrum of use covering the entire gestation period, its excellent efficacy, especially when given before 25 d post-mating, and its very high innocuity.