Long term outcome of severe mitral regurgitation after percutaneous mitralvalvuloplasty

Percutaneous mitral valvuloplasty has become the technique of choice for mi tral estenosis with favorable anatomic features. However, mitral regurgitat ion is an important complication of this technique that has not reduced wit h Inoue technique. This study reports the clinical and echocardiographic follow-up (28 +/- 20 months) of 20 patients who developed severe mitral regurgitation after perc utaneous mitral valvuloplasty with Inoue technique. The patients were divid ed into two groups on the basis of the need for mitral valve replacement du ring follow-up. We analyzed variables before and after percutaneous mitral valvuloplasty using univariate analysis. Multivariate analysis was performe d to identify variables as independent predictors of the need for mitral va lve replacement. Ten patients needed mitral valve replacement during follow-up. Multivariate analysis showed that suboptimal result of percutaneous mitral valvuloplast y (MVA < 1.5 cm(2)) was the only independent predictor of the need of mitra l valve replacement. We concluded that the need for MVR in patients who develop severe mitral re gurgitation after percutaneous mitral valvuloplasty was related to suboptim al result of procedure.