Adult pleuropulmonary blastoma is an uncommon mesenchymal tumor of the peri
pheral lung parenchyma composed of undifferentiated cells. The differential
diagnosis with Askin-Rosai's tumor, an extrapulmonary pleuroparietal neuro
ectodermal tumor, may De a difficult task. We propose a similar therapeutic
approach for these two malignant conditions. surgical excision associated
with chemotherapy and autologous bone marrow transplant with adjuvant radio
therapy in case of recurrence. These two entities have many epidemiological
, clinical, histological and immunohistochemical similarities.