Increased prevalence of urinary tract infections and anomalies in infants with pyloric stenosis

We performed a retrospective analysis of all patients admitted to our insti tution with a diagnosis of infantile hypertrophic pyloric stenosis (MPS) du ring a 10-year period from 1985-95 in order to assess the possible associat ion between IHPS and urinary tract infections (UTIs), All 285 patients with IHPS had radiological or ultrasonographic confirmation of that diagnosis a nd underwent the Ramstedt procedure. Those who continued to be symptomatic were evaluated for UTI by urine analysis and culture. Positive cases were f urther evaluated for urinary system anomalies. The male:female ratio of IHP S was 3.4:1. Concomitant UTI was diagnosed in 8 patients by suprapubic aspi ration or bladder catheterization. The prevalence of UTI in this series was 2.8%, 20-fold higher than the expected prevalence. Three of the 8 patients with UTI (37.5%) had urinary tract anomalies. These findings suggest an as sociation between IHPS and UTI. We recommend that all IHPS patients be eval uated for UTI and positive cases undergo further evaluation for urinary ano malies.