Attenuated total reflection mid-infrared spectroscopy for clinical chemistry applications using silver halide fibers

The quantitative analysis of biotic fluids can be carried out using attenua ted total reflection mid-infrared spectroscopy based on silver halide fiber s, because good optical throughput can be achieved especially in the finger print region of the mid-infrared spectral range. The advantages and prospec ts of this technique using biofluids or dry films, obtained from such aqueo us solutions, are discussed in the context of developing routine assay meth odology for the analysis of biofluids submitted to the clinical laboratory for analysis. Accessories developed from such fibers are simple and less ex pensive than conventional equipment using classical infrared waveguides. Ex amples are also given for fiber application in gas analysis. (C) 1998 Elsev ier Science S.A. All rights reserved.