TCI remifentanil - implications for intra- and postoperative use

Remifentanil, the latest development among the fentanyl congeners, offers a dvantages for modern anaesthetic practice. Its application by manual infusi on, however, is characterised by some disadvantages. A target-controlled in fusion of remifentanil that is based on population pharmacokinetics is intr oduced and discussed as being superior to manual application in terms of ac curacy, individual adaption and safety both during anaesthesia and the tran sition to the early postoperative period.