Solution phase synthesis of potential DNA-binding molecules based on the PNA backbone

Authors
Challa, H Woski, SA
Citation
H. Challa et Sa. Woski, Solution phase synthesis of potential DNA-binding molecules based on the PNA backbone, TETRAHEDR L, 40(3), 1999, pp. 419-422
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
3
Year of publication
1999
Pages
419 - 422
Database
ISI
SICI code
0040-4039(19990115)40:3<419:SPSOPD>2.0.ZU;2-K
Abstract
The N-(2-aminoethyl)glycine backbone unit of PNA has been derivatized with pyreneacetic acid and acetic acid moieties to produce monomers for the synt hesis of potential polyintercalators. Short oligomers containing these resi dues have been assembled using solution phase coupling reactions. (C) 1998 Elsevier Science Ltd. All rights reserved.