We describe experience with 6 cases of methamphetamine overdose. Because of
its low cost, easy availability and longer duration of action compared to
cocaine, methamphetamine has become the drug of choice in Various communiti
es. Marked change in mental status was observed in all of our patients. One
patient had a myocardial infarction that responded well to thrombolytic th
erapy. Clinicians should be familiar with the medical effects and treatment
of acute methamphetamine toxicity.