Effects of dopamine and aminophylline on contrast-induced acute renal failure after coronary angioplasty in patients with preexisting renal insufficiency

Authors
Abizaid, AS Clark, CE Mintz, GS Dosa, S Popma, JJ Pichard, D Satler, LF Harvey, M Kent, KM Leon, MB
Citation
As. Abizaid et al., Effects of dopamine and aminophylline on contrast-induced acute renal failure after coronary angioplasty in patients with preexisting renal insufficiency, AM J CARD, 83(2), 1999, pp. 260
Citations number
28
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
83
Issue
2
Year of publication
1999
Database
ISI
SICI code
0002-9149(19990115)83:2<260:EODAAO>2.0.ZU;2-0
Abstract
In phase 1 of this study, 60 patients undergoing coronary angioplasty were randomized to receive saline, dopamine, or aminophylline; the overall incid ence of contrast-induced renal failure was 38%, without difference among th e 3 groups. In phase 2 of this study, 72 patients with established contrast -induced renal failure were randomized to receive saline or dopamine; dopam ine had a deleterious effect on the severity of renal failure, prolonging t he course.