Effective dose range of candesartan cilexetil for systemic hypertension

Authors
Bell, TP DeQuattro, V Lasseter, KC Ruff, D Hardison, JD Cushing, D Kezer, AE Michelson, EL
Citation
Tp. Bell et al., Effective dose range of candesartan cilexetil for systemic hypertension, AM J CARD, 83(2), 1999, pp. 272
Citations number
6
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
83
Issue
2
Year of publication
1999
Database
ISI
SICI code
0002-9149(19990115)83:2<272:EDROCC>2.0.ZU;2-6
Abstract
The results of this randomized, double-blind, placebo-controlled, forced-do se titration study in a diverse population of hypertensive patients in the US indicate that candesartan cilexetil has clinically meaningful dose-relat ed blood pressure-lowering effects and that maximum blood pressure reductio n is achieved with doses of 16 and 32 mg given once daily. This study confi rms that candesartan cilexetil is a highly effective antihypertensive agent with an excellent tolerability and safety profile, without dose-related ad verse effects.