BACKGROUND: Routine endocrine screening of idiopathic gynecomastia has been
advocated, but may not be cost effective. We carried out a cost-benefit an
alysis of this approach.
METHODS: A retrospective study (1992 to 1997) of 87 adult males with sympto
matic gynecomastia was performed.
RESULTS: Thirty-four (39%) patients had extrinsic causes; 53 (61%) were con
sidered idiopathic. Forty-five idiopathic cases underwent endocrine testing
: beta human chorionic gonadotropin alone, 16; and beta human chorionic gon
adotropin, LH, estradiol, testosterone +/- testicular ultrasound, 29. One (
2%) occult Leydig cell testicular tumor was detected. Forty-four patients h
ad normal studies and remain well after local excision.
CONCLUSION: Routine endocrine evaluation of idiopathic gynecomastia is rare
ly productive; such testing is best done selectively. Am J Surg. 1998;176:6
38-641. (C) 1998 by Excerpta Medica, Inc.