A familiar form of keratosis punctata of the palmar and soles creases

Background. Keratosis punctata of the palmar creases is a variant of puncta ta palmoplantar keratoderma. Case report. keratosis punctata of the palmar creases was observed in a 53 year-old North African male. The lesions presented as small keratotic papul es confined exclusively to the flexion creases of the palms and digits, wit h a bilateral localization on the soles. The lesions were sensitive to pres sure. The proband's 19 year-old son had similar lesions. Discussion. Keratosis punctata of the palmar creases is characterized by th e development of small round keratotic papules, electively and exclusively found in the palmar, digital, and uncommonly soles creases. The etiology is unknown. The frequency is higher in the black. population. Although consid ered as an hereditary palmoplantar keratoderma with autosomal dominant tran smission, familial cases with localizations on the soles is uncommon.