Immunocytochemical demonstration of reduced glutathione in neurons of rat forebrain

Authors
Maybodi, L Pow, DV Kharazia, VN Weinberg, RJ
Citation
L. Maybodi et al., Immunocytochemical demonstration of reduced glutathione in neurons of rat forebrain, BRAIN RES, 817(1-2), 1999, pp. 199-205
Citations number
37
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993 → ACNP
Volume
817
Issue
1-2
Year of publication
1999
Pages
199 - 205
Database
ISI
SICI code
0006-8993(19990130)817:1-2<199:IDORGI>2.0.ZU;2-X
Abstract
Histochemical studies show reduced glutathione (GSH) in neuroglia, whereas immunocytochemistry of glutaraldehyde-fixed tissue reveals GSH also in neur ons. Using an antibody suitable for formaldehyde-fixed tissue, we find GSH staining in the cytoplasm of neurons throughout the brain. Staining was pro minent in large pyramidal neurons of cerebral cortex, in basal ganglia, and in reticular and ventrobasal thalamic nuclei. (C) 1999 Elsevier Science B. V.