Effects of fluoxetine administration on mu-opoid receptor immunostaining in the rat forebrain

Authors
de Gandarias, JM Echevarria, E Acebes, I Abecia, LC Casis, O Casis, L
Citation
Jm. De Gandarias et al., Effects of fluoxetine administration on mu-opoid receptor immunostaining in the rat forebrain, BRAIN RES, 817(1-2), 1999, pp. 236-240
Citations number
19
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH
ISSN journal
00068993 → ACNP
Volume
817
Issue
1-2
Year of publication
1999
Pages
236 - 240
Database
ISI
SICI code
0006-8993(19990130)817:1-2<236:EOFAOM>2.0.ZU;2-R
Abstract
Fluoxetine is a selective serotonin reuptake inhibitor. Analysis of mu-opio id receptor immunostaining after chronic fluoxetine administration in rats revealed an increase in the density of cells expressing mu-opioid receptors in the caudatus-putamen, the dentate gyrus, the lateral septum and the fro ntal, parietal and piriform cortices. These data suggest that mu-opioid rec eptor expression in the rat forebrain is altered by in vivo chronic fluoxet ine treatment. (C) 1999 Elsevier Science B.V.