Jm. De Gandarias et al., Effects of fluoxetine administration on mu-opoid receptor immunostaining in the rat forebrain, BRAIN RES, 817(1-2), 1999, pp. 236-240
Fluoxetine is a selective serotonin reuptake inhibitor. Analysis of mu-opio
id receptor immunostaining after chronic fluoxetine administration in rats
revealed an increase in the density of cells expressing mu-opioid receptors
in the caudatus-putamen, the dentate gyrus, the lateral septum and the fro
ntal, parietal and piriform cortices. These data suggest that mu-opioid rec
eptor expression in the rat forebrain is altered by in vivo chronic fluoxet
ine treatment. (C) 1999 Elsevier Science B.V.