In New Zealand white rabbits, cholera-toxin HRP was injected into the carot
id sinus nerve just proximal to the carotid sinus. After survival periods o
f 3-5 days the rabbits were anesthetized and the brain fixed with aldehyde
solution. Transverse sections were cut on a sledge microtome and the sectio
ns reacted with the tetramethylbenzidine procedure. HRP-positive fibers ent
ered the ipsilateral dorsolateral medulla at the level of the acoustic tube
rcle, joining the tractus solitarius. Positive fibres were found principall
y ipsilaterally in four regions of the medulla: in the caudal two thirds of
the nucleus tractus solitarius, in its dorsolateral regions and, more caud
ally, in its commissural subdivision; in the dorsolateral aspect of the spi
nal nucleus of the trigeminal nerve; in the region ventral and ventrolatera
l to the tractus solitarius (extending beyond the nucleus tractus solitariu
s); and in the ventrolateral medulla oblongata. (C) 1999 Elsevier Science B
.V. All rights reserved.