Capillary electrophoretic separation of mono- and dimaltosyl-beta-cyclodextrins and determination of the stability constants of their benzoate complexes

Capillary zone electrophoresis method has been developed for the separation (and determination) of mono- and dimaltosyl-beta-cyclodextrins using indir ect UV absorbance detection. The separation is based on inclusion complex f ormation with benzoate ion which is used as background electrolyte and abso rbance provider simultaneously. Good resolution of cyclodextrin mixtures ca n be achieved optimizing the pH and the benzoic acid concentration in the b ackground electrolyte. Capillary zone electrophoresis method has also been developed for the determination of formation constants of inclusion complex es.