Conservative treatment in primary neonatal megaureter

The authors report their experience on 22 neonates (14 males and 8 females) with primary megaureter. In 18 patients a prenatal diagnosis was available , in the other four the diagnosis was suspected during a neonatal ultrasoun d screening. The dilatation involved the right ureter 7 times and the left 13 times, in 2 patients it was bilateral. Intravenous urography documented a type I ureteral dilatation in 2 renal units (8.3 %), a type II in 9 (37.5 %) and a type III dilatation in 13 (54.2 %). Radionuclide scan (Tc-99m DTP A) demonstrated in all the renal units with megaureter a stable function. F rom diuretic renal scan, non-obstruction appeared in 19 (83 %), obstruction in 2 (8.5 %) and an equivocal result in the remaining 2. Antibiotic prophy laxis was administered to all patients. Follow-up period ranged from 18 to 54 months. The 2 obstructed megaureter were surgically treated. Other 2 pat ients with type III dilatation and nonobstructing megaureter underwent surg ery at 18 and 24 months of age respectively. The remaining 17 patients were all conservatively treated. The 2 patients with type I dilatation resolved spontaneously. Of 9 patients with type II megaureter the dilatation resolv ed in 6 patients and 3 patients had a good reduction. In the remaining 8 pa tients with type III megaureter, the dilatation resolved in 5 cases and 3 p atients had only a fair reduction. The renal function (> 40 %) remained sta ble in all the patients.