Ya. Popov et al., Molecular genetic analysis of DNA structure of pFra plasmids in plague causative agents of different biovares, GENETIKA, 34(2), 1998, pp. 198-205
Data on comparative molecular genetic analysis of pFra plasmids from plague
bacillus belonging to either two biovares (antiqua and orientalis) are pre
sented. It was established that during evolution these replicons were rearr
anged, which resulted in the differences between pFra plasmids of plague ba
cillus of antiqua biovare (Yersinia pestis 231 and Y. pestis 358/12) and th
at of orientalis biovare (Y. pestis A1122 and Y. pestis EV). These included
inversions of two plasmid DNA regions and size differences of 3 kb.