Management and prognosis of primary Fallopian tube carcinoma

Citation
Ac. Rosen et al., Management and prognosis of primary Fallopian tube carcinoma, GYNECOL OBS, 47(1), 1999, pp. 45-51
Citations number
30
Categorie Soggetti
da verificare
Journal title
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
ISSN journal
03787346 → ACNP
Volume
47
Issue
1
Year of publication
1999
Pages
45 - 51
Database
ISI
SICI code
0378-7346(1999)47:1<45:MAPOPF>2.0.ZU;2-E
Abstract
We retrospectively analyzed 143 women treated in 28 departments from 1980 t o 1995, to study the impact of prognostic factors in primary carcinoma of t he fallopian tube. Further aims of the study were to evaluate the treatment of fallopian tube carcinoma in Austria. Staging of disease was done accord ing to the modified FIGO system, and grading according to the criteria sugg ested by Hu et at. The mean age of the patients was 62.5 years. Sixty (42%) tumors were found to be in stage I, 28 (19%) in stage II, 38 (27%) in stag e III, and 17 (12%) in stage IV. Radical resection was achieved in 102 (71% ) patients. In 122 (85%) women surgery involved removal of the uterus, the adnexa, and/or the omentum or lymph nodes. Postoperatively patients underwe nt adjuvant therapy consisting of either irradiation (n = 40; 28%) or chemo therapy (n = 70; 49%); 33 women (23%) did not receive any treatment after s urgery. The 5-year survival rate for all stages of disease was 43%. The 5-y ear survival rate was 59% for stages I and II and 19% for stages III and IV . FIGO stage, histologic grading and residual tumor showed an independent p rognostic impact in multivariate analysis.