Regulation of MHC class I gene expression: A case study

Authors
Singer, DS Howcroft, TK Weissman, J Brown, J Kirshner, S Mozes, E Kohn, LD
Citation
Ds. Singer et al., Regulation of MHC class I gene expression: A case study, IMMUNOLOGIS, 6(6), 1998, pp. 214-219
Citations number
40
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGIST
ISSN journal
11925612 → ACNP
Volume
6
Issue
6
Year of publication
1998
Pages
214 - 219
Database
ISI
SICI code
1192-5612(199811/12)6:6<214:ROMCIG>2.0.ZU;2-5
Abstract
MHC class I gene transcription is tightly regulated, Here, Dinah S, Singer and colleagues describe the complex mechanisms involved and propose that ov erexpression may lead to autoimmune disease,while underexpression may lead to unchecked viral infections.