Imparting recognition sites in poly(HEMA) for two compounds through molecular imprinting

So far, molecularly imprinted polymers (MIPs) have been synthesized and eva luated as selective matrices for single components. It may be possible to i mpart multiple recognition sites in MIPs, which could be used as elements c apable of binding more than one component. Such systems could advantageousl y be used in the design of sensors having the ability to sense more than on e compound at a time. This communication discusses such a possibility by im printing sites for two model compounds, namely, salicylic acid and hydrocor tisone in poly(2-hydroxy ethyl methacrylate). (C) 1999 John Wiley & Sons, I nc.