Crystal structure of the cytotoxic marine alkaloid 2-bromoleptoclinidinone

Authors
Lindsay, BS Oliver, AG Rickard, CEF Copp, BR
Citation
Bs. Lindsay et al., Crystal structure of the cytotoxic marine alkaloid 2-bromoleptoclinidinone, J CHEM CRYS, 28(8), 1998, pp. 645-648
Citations number
14
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF CHEMICAL CRYSTALLOGRAPHY
ISSN journal
10741542 → ACNP
Volume
28
Issue
8
Year of publication
1998
Pages
645 - 648
Database
ISI
SICI code
1074-1542(199808)28:8<645:CSOTCM>2.0.ZU;2-F
Abstract
2-Bromoleptoclinidinone methanol solvate, C18H8BrN3O . CH4O, crystallizes i n the orthorhombic space group Pbca with a = 15.7013(2), b = 7.3308(1), and c = 26.9326(1) Angstrom. The molecule is essentially planar, with the larg est deviations occurring at bromine (-0.21 Angstrom), carbonyl oxygen O(1) (+0.19 Angstrom) and in ring-A (C(9) -0.15 Angstrom, C(10) -0.15 Angstrom). Methanol occupies the 1,10-phenanthroline-like metal binding site of the t itle compound.